The SANDWICH Trial

This research project will evaluate a protocol-based quality improvement bundle for reducing the duration of invasive mechanical ventilation.

Weaning from ventilation is a complex process involving several stages that include recognition of patient readiness to begin the weaning process; steps to reduce ventilation while optimising sedation in order not to induce distress; and removing the endotracheal tube. Delay at any stage can prolong the duration of mechanical ventilation. The SANDWICH Quality Improvement bundle is a multi-component intervention targeted at helping clinicians to safely expedite this process and minimise the harms associated with unnecessary invasive mechanical ventilation.